MIR205HG

Across TCGA pan-cancer cohorts, MIR205HG RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of MIR205HG’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR205HG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR205HG is over-expressed in tumor, although a few such as BRCA and KIRC show the opposite, repressed pattern.

LUSC, UCEC, and BRCA are the cancer types where MIR205HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR205HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+4.578	<.001	7	view →
UCEC	All	All	+2.034	<.001	6	view →
BRCA	All	III,IV	−2.000	<.001	6	view →
HNSC	All	All	+0.735	.003	6	view →
KIRC	Female	All	−0.393	.019	3	view →
PAAD	All	All	+4.367	.013	2	view →
BLCA	All	All	+1.758	.043	2	view →
PRAD	All	All	−1.710	<.001	2	view →
THCA	All	All	+0.340	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

MIR205HG–LUSC

Open the LUSC breakdown →