Q-omics provides the consensus-scored MIR148A profile across patient tissues and cancer cell-line models. MIR148A expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, MIR148A is differentially expressed in 13, with the highest sampling consensus in COAD. Additionally, MIR148A RNA expression shows 14,558 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight COAD, and UVM as cancer lineages where MIR148A shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR148A — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR148A survival associations across molecular data types. MIR148A RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR148A RNA expression–survival associations across cancer types. High MIR148A expression shows unfavorable associations in COAD, LGG and KIRC, but favorable associations in MESO, LUAD and UCS. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for MIR148A RNA expression.
This table summarizes MIR148A tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for MIR148A. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR148A shows higher tumor expression in COAD, HNSC, BRCA, BLCA, LIHC and LUSC. The COAD box plot shows higher MIR148A RNA expression in tumor versus normal tissue (log2 FC = +1.066, t-test p < 0.001).
This table shows molecular features associated with MIR148A in patient tissues and cancer cell lines. In patient samples, MIR148A shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
