Across TCGA pan-cancer cohorts, MIR148A RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MIR148A data layer.
The strongest signal is observed in colon adenocarcinoma (COAD), where higher MIR148A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR148A expression acts as an unfavorable survival marker, although some lineages such as MESO and LUAD show a favorable association.
COAD, MESO, and LGG are the cancer types where MIR148A RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.