Across TCGA patient cohorts, MIR1-1 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible MIR1-1-associated genes across cancer lineages are IGHVII-67-1, OR4K16P, and KRTAP12-6P. Each is linked with MIR1-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR1-1-to-partner and partner-to-MIR1-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR1-1→partner) and Y-score (partner→MIR1-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	IGHVII-67-1 →	+0.591	+7.640	<.001	.009	3	1
BLCA	OR4K16P →	+0.039	+7.640	<.001	.009	3	1
BLCA	KRTAP12-6P →	+0.189	+7.640	<.001	.009	3	1
BLCA	RNU6-839P →	+0.313	+7.640	<.001	.009	3	1
BLCA	RN7SKP6 →	+0.119	+7.640	<.001	.009	3	1
BLCA	MIR521-1 →	+0.367	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

MIR1-1 survival (RNA) · tumor vs normal (RNA) · all MIR1-1 data types