MIR521-1

Q-omics provides the consensus-scored MIR521-1 profile across patient tissues and cancer cell-line models. MIR521-1 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, MIR521-1 RNA expression shows 8,631 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight ESCA, and TGCT as cancer lineages where MIR521-1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes MIR521-1 survival associations across molecular data types. MIR521-1 RNA expression shows survival associations in the most cancer types (6), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR521-1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	ESCA (39)	view →
Mutation	Kaplan–Meier	2	SKCM (24)	view →

This table ranks reproducible MIR521-1 RNA expression–survival associations across cancer types. High MIR521-1 expression shows unfavorable associations in ESCA, THYM, BLCA, LAML and SKCM, but favorable associations in STAD. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify ESCA as the clearest survival context for MIR521-1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	All	0.198	0.872	.003	39	view →
STAD	OS	Tertile	IV	1.000	0.277	.023	36	view →
THYM	OS	Tertile	All	0.534	0.977	<.001	36	view →
BLCA	DFS	Tertile	III,IV	0.078	0.548	<.001	18	view →
LAML	DFS	Tertile	All	0.112	0.579	.002	18	view →
SKCM	DFS	Tertile	III,IV	0.219	0.599	.030	9	view →

Pink = unfavorable, green = favorable. all 6 lineages →

MIR521-1-ESCA (OS)

Explore this curve interactively →