MINDY3

Across TCGA patient cohorts, MINDY3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,380 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MINDY3-associated genes across cancer lineages are EIF2AK2, LINC01703, and SEPTIN7P13. Each is linked with MINDY3 in more than 3 cancer types. Because this analysis shows association rather than direction, both MINDY3-to-partner and partner-to-MINDY3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MINDY3 versus EIF2AK2 in LSCC, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MINDY3→partner) and Y-score (partner→MINDY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EIF2AK2 →	-0.424	-0.265	.003	.003	3	4
LSCC	LINC01703 →	-0.996	-0.356	<.001	<.001	3	3
HNSC	SEPTIN7P13 →	-0.538	-0.258	.001	<.001	3	3
GBM	HBA2 →	+1.553	+0.308	<.001	<.001	3	3
GBM	HBB →	+1.495	+0.293	<.001	<.001	3	3
BRCA	ARHGAP12 →	+0.656	+0.447	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,380 associations by consensus.

MINDY3 vs EIF2AK2 — LSCC

Explore this scatter interactively →