MINDY3

Across TCGA cell cohorts, MINDY3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,856 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MINDY3-associated GO terms across cancer lineages are Regulation of tRNA catabolic process, Negative regulation of tRNA catabolic process, and Regulation of tRNA stability. Each is linked with MINDY3 in more than 11 cancer types. Because this analysis shows association rather than direction, both MINDY3-to-partner and partner-to-MINDY3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tRNA catabolic process grouped by MINDY3-low versus MINDY3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MINDY3→partner) and Y-score (partner→MINDY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of tRNA catabolic process →	-0.153	-0.903	.001	<.001	3	12
PANCREAS	Negative regulation of tRNA catabolic process →	-0.153	-0.903	.001	<.001	3	12
PANCREAS	Regulation of tRNA stability →	-0.153	-0.903	.001	<.001	3	12
PANCREAS	tRNA stabilization →	-0.153	-0.903	.001	<.001	3	12
SOFT_TISSUE	Golgi organization →	+0.063	+0.667	<.001	<.001	3	9
BLOOD_Leukemia	Post-Golgi vesicle-mediated transport →	+0.047	+0.677	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,856 associations by consensus.

Regulation of tRNA catabolic process by MINDY3 expression — PANCREAS

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