MIF4GD

Across TCGA patient cohorts, MIF4GD mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIF4GD-associated genes across cancer lineages are Erythrocytes, CD8+ naive T-cells, and Endothelial cells. Each is linked with MIF4GD in more than 1 cancer types. Because this analysis shows association rather than direction, both MIF4GD-to-partner and partner-to-MIF4GD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by MIF4GD-low versus MIF4GD-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIF4GD→partner) and Y-score (partner→MIF4GD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.039	+3.180	<.001	.010	3	2
UCEC	CD8+ naive T-cells →	+0.029	+3.338	.013	.005	3	1
UCEC	Endothelial cells →	-0.044	-2.764	.008	.003	3	1
UCEC	lymphatic Endothelial cells →	-0.025	-3.290	.015	.010	3	1
UCEC	Mesangial cells →	-0.048	-2.104	.004	.019	3	1
UCEC	mv Endothelial cells →	-0.028	-2.584	.005	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Erythrocytes by MIF4GD expression — UCEC

Explore this box plot interactively →