MIF4GD

Across TCGA pan-cancer cohorts, MIF4GD RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MIF4GD data layer compared with 5 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MIF4GD RNA is associated with better overall survival. In most high-consensus cancer types, elevated MIF4GD expression acts as an unfavorable survival marker, although some lineages such as UCEC and BRCA show a favorable association.

UCEC, BRCA, and KIRC are the cancer types where MIF4GD RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.724	0.460	.003	58	view →
BRCA	OS	Tertile	III,IV	0.948	0.832	<.001	50	view →
KIRC	DFS	Quartile	III,IV	0.761	0.405	.006	34	view →
SARC	OS	Tertile	All	0.835	0.659	.001	31	view →
LIHC	DFS	Tertile	All	0.294	0.634	<.001	27	view →
PAAD	OS	Quartile	All	0.598	0.325	.005	24	view →
LUAD	OS	Median	II,III,IV	0.539	0.344	.009	19	view →
SKCM	DFS	Tertile	II,III,IV	0.325	0.157	.004	18	view →
LUSC	OS	Tertile	All	0.830	0.711	.010	17	view →
MESO	DFS	Quartile	II,III,IV	0.280	0.786	.006	15	view →
HNSC	DFS	Tertile	IV	0.399	0.233	.018	14	view →
READ	DFS	Quartile	All	0.858	0.600	.018	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MIF4GD–UCEC (OS)

Open the UCEC breakdown →