MIF

Across TCGA patient cohorts, MIF protein abundance is significantly associated with the RNA expression of many other genes, with 9,043 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MIF-associated genes across cancer lineages are CBY1, SRRD, and SLC25A1. Each is linked with MIF in more than 5 cancer types. Because this analysis shows association rather than direction, both MIF-to-partner and partner-to-MIF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIF versus CBY1 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIF→partner) and Y-score (partner→MIF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CBY1 →	+0.591	+0.303	<.001	<.001	3	5
HNSC	SRRD →	+0.571	+0.246	.002	.007	2	6
UCEC	SLC25A1 →	+0.668	+0.157	.001	.002	3	4
UCEC	PMM1 →	+0.468	+0.178	.007	<.001	3	4
LSCC	P4HA1 →	+0.666	+0.252	<.001	.001	3	4
UCEC	MIR210HG →	+1.107	+0.273	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,043 associations by consensus.

MIF vs CBY1 — UCEC

Explore this scatter interactively →