MIA2

Across TCGA patient cohorts, MIA2 mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MIA2-associated genes across cancer lineages are MIR944, DUX4L19, and MIR7973-1. Each is linked with MIA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIA2-to-partner and partner-to-MIA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR944 grouped by MIA2-low versus MIA2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIA2→partner) and Y-score (partner→MIA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR944 →	+1.591	+7.741	<.001	.009	3	2
COAD	DUX4L19 →	+0.039	+7.741	<.001	.009	3	2
UCEC	MIR7973-1 →	+0.903	+4.943	<.001	<.001	3	1
UCEC	MIR6075 →	+0.628	+4.223	<.001	.003	3	1
UCEC	HNRNPCL3 →	+0.099	+3.778	<.001	.007	3	1
UCEC	BCRP6 →	+0.134	+3.661	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

MIR944 by MIA2 expression — COAD

Explore this box plot interactively →