MIA-RAB4B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIA-RAB4B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,677 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MIA-RAB4B-associated GO terms across cancer lineages are Positive regulation of DNA repair, Negative regulation of mRNA processing, and Positive regulation of DNA metabolic process. Each is linked with MIA-RAB4B in more than 12 cancer types. Because this analysis shows association rather than direction, both MIA-RAB4B-to-partner and partner-to-MIA-RAB4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by MIA-RAB4B-low versus MIA-RAB4B-high in LIHC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIA-RAB4B→partner) and Y-score (partner→MIA-RAB4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCPositive regulation of DNA repair →+0.023+0.022<.001<.001313
KIRCNegative regulation of mRNA processing →+0.040+0.014<.001<.001312
GBMPositive regulation of DNA metabolic process →+0.025+0.143<.001<.001312
ACCCytoplasmic translation →+0.033+0.027.001.001311
UVMObsolete nuclear-transcribed mRNA catabolic process, exonucleolytic →+0.032+0.106.007.004212
LIHCPositive regulation of DNA-templated transcription, elongation →+0.026+0.022<.001<.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,677 associations by consensus.

Positive regulation of DNA repair by MIA-RAB4B expression — LIHC

Box plot of Positive regulation of DNA repair in MIA-RAB4B-low vs MIA-RAB4B-high samples in LIHC.

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Exploration