MIA-RAB4B

Across TCGA pan-cancer cohorts, MIA-RAB4B RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MIA-RAB4B data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher MIA-RAB4B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIA-RAB4B expression acts as an unfavorable survival marker, although some lineages such as CHOL and SKCM show a favorable association.

KIRP, LIHC, and KIRC are the cancer types where MIA-RAB4B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	III,IV	0.040	0.691	<.001	99	view →
LIHC	OS	Tertile	All	0.309	0.539	<.001	81	view →
KIRC	OS	Tertile	All	0.689	0.830	.002	54	view →
CHOL	DFS	Median	III,IV	0.647	0.127	.006	42	view →
DLBC	OS	Quartile	II,III,IV	0.405	0.865	.001	41	view →
LGG	DFS	Tertile	All	0.632	0.774	<.001	37	view →
PRAD	OS	Tertile	All	0.981	1.000	<.001	36	view →
BRCA	OS	Tertile	IV	0.287	0.748	.003	35	view →
ACC	DFS	Tertile	All	0.127	0.622	<.001	30	view →
KICH	OS	Tertile	II,III,IV	0.335	0.864	.004	27	view →
SKCM	OS	Quartile	All	0.373	0.210	.007	21	view →
THCA	OS	Tertile	II,III,IV	0.905	0.990	.006	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MIA-RAB4B–KIRP (DFS)

Open the KIRP breakdown →