MHENCR

Across TCGA patient cohorts, MHENCR RNA expression is significantly associated with the go_rna of many other GO terms, with 7,169 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible MHENCR-associated GO terms across cancer lineages are Base-excision repair, AP site formation, Depyrimidination, and Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'. Each is linked with MHENCR in more than 27 cancer types. Because this analysis shows association rather than direction, both MHENCR-to-partner and partner-to-MHENCR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Base-excision repair, AP site formation grouped by MHENCR-low versus MHENCR-high in KIRP.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MHENCR→partner) and Y-score (partner→MHENCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	Base-excision repair, AP site formation →	+0.087	+1.262	<.001	<.001	3	28
KIRC	Depyrimidination →	+0.071	+1.124	<.001	<.001	3	27
UVM	Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' →	+0.060	+0.729	<.001	.002	3	26
ACC	Regulation of DNA-directed DNA polymerase activity →	+0.071	+1.134	<.001	<.001	3	26
KIRC	Mitochondrial respiratory chain complex assembly →	+0.043	+1.021	<.001	<.001	3	25
ESCA	Oxidative phosphorylation →	+0.050	+0.706	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,169 associations by consensus.

Base-excision repair, AP site formation by MHENCR expression — KIRP

Explore this box plot interactively →