melanoma highly expressed competing endogenous lncRNA for miR-425 and miR-489Genealiases: []
Q-omics provides the consensus-scored MHENCR profile across patient tissues and cancer cell-line models. MHENCR expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, MHENCR is differentially expressed in 15, with the highest sampling consensus in COAD. Additionally, MHENCR RNA expression shows 17,088 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, COAD, and THYM as cancer lineages where MHENCR shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MHENCR — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MHENCR survival associations across molecular data types. MHENCR RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MHENCR RNA expression–survival associations across cancer types. High MHENCR expression shows unfavorable associations in KIRC and ACC, but favorable associations in PAAD, READ, BLCA and THYM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for MHENCR RNA expression.
This table summarizes MHENCR tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for MHENCR. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MHENCR shows lower tumor expression in THCA and KICH and higher tumor expression in COAD, LIHC, HNSC and STAD. The COAD box plot shows higher MHENCR RNA expression in tumor versus normal tissue (log2 FC = +1.842, t-test p < 0.001).
This table shows molecular features associated with MHENCR in patient tissues and cancer cell lines. In patient samples, MHENCR shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
