MHENCR

Across TCGA pan-cancer cohorts, MHENCR RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MHENCR data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MHENCR RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MHENCR expression acts as an unfavorable survival marker, although some lineages such as PAAD and READ show a favorable association.

KIRC, ACC, and PAAD are the cancer types where MHENCR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.507	0.712	<.001	127	view →
ACC	DFS	Tertile	All	0.243	0.681	<.001	104	view →
PAAD	OS	Median	All	0.556	0.245	<.001	56	view →
READ	OS	Median	III,IV	0.641	0.281	.008	37	view →
BLCA	DFS	Median	II,III,IV	0.660	0.566	.011	24	view →
THYM	OS	Median	All	0.965	0.742	.005	22	view →
LUAD	OS	Tertile	All	0.866	0.769	.003	21	view →
UVM	OS	Tertile	III,IV	0.276	1.000	.014	18	view →
PRAD	DFS	Median	All	0.843	0.923	.003	18	view →
COAD	OS	Quartile	III,IV	0.676	0.929	.013	16	view →
LIHC	DFS	Tertile	All	0.464	0.617	.005	16	view →
SKCM	DFS	Median	III,IV	0.366	0.661	.004	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MHENCR–KIRC (DFS)

Open the KIRC breakdown →