MGRN1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MGRN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,901 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MGRN1-associated GO terms across cancer lineages are Positive regulation of response to food, Positive regulation of appetite, and Positive regulation of response to nutrient levels. Each is linked with MGRN1 in more than 16 cancer types. Because this analysis shows association rather than direction, both MGRN1-to-partner and partner-to-MGRN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of response to food grouped by MGRN1-low versus MGRN1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MGRN1→partner) and Y-score (partner→MGRN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTPositive regulation of response to food →+1.012+0.885<.001.001317
UPPER_AERODIGESTIVE_TRACTPositive regulation of appetite →+1.012+0.885<.001.001317
UPPER_AERODIGESTIVE_TRACTPositive regulation of response to nutrient levels →+1.038+0.829<.001.003316
LUNG_SCLCSymbiont-mediated disruption of host cell PML body →+0.130+0.856<.001<.001314
LUNG_NSCLC_LUSCCalcium-independent cell-matrix adhesion →+0.172+1.026.004.002314
BONECAMP/PKA signal transduction →+0.170+0.745<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,901 associations by consensus.

Positive regulation of response to food by MGRN1 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Positive regulation of response to food in MGRN1-low vs MGRN1-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration