MGAT4B

Across TCGA patient cohorts, MGAT4B mutation is significantly associated with the RNA expression of many other genes, with 1,135 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MGAT4B-associated genes across cancer lineages are RNU7-149P, ARHGAP16P, and RN7SL813P. Each is linked with MGAT4B in more than 1 cancer types. Because this analysis shows association rather than direction, both MGAT4B-to-partner and partner-to-MGAT4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-149P grouped by MGAT4B-low versus MGAT4B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT4B→partner) and Y-score (partner→MGAT4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU7-149P →	+0.526	+5.070	<.001	.008	3	2
KIRP	ARHGAP16P →	+0.035	+6.301	<.001	.001	3	2
SKCM	RN7SL813P →	+0.126	+4.970	<.001	.005	3	2
BLCA	MIR4299 →	+0.341	+5.229	<.001	.002	3	2
KIRP	LINC01728 →	+0.097	+5.264	<.001	.006	3	2
KIRP	GYG1P2 →	+0.089	+5.376	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,135 associations by consensus.

RNU7-149P by MGAT4B expression — BRCA

Explore this box plot interactively →