MGAT4B

Across TCGA cell cohorts, MGAT4B mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MGAT4B-associated genes across cancer lineages are OR6T1, OR6M1, and OR2A25. Each is linked with MGAT4B in more than 1 cancer types. Because this analysis shows association rather than direction, both MGAT4B-to-partner and partner-to-MGAT4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6T1 grouped by MGAT4B-low versus MGAT4B-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT4B→partner) and Y-score (partner→MGAT4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR6T1 →	+0.084	+4.285	<.001	.007	3	1
STOMACH	OR6M1 →	+0.050	+4.285	<.001	.007	3	1
STOMACH	OR2A25 →	+0.023	+4.129	.002	.007	3	1
BLOOD_Leukemia	SYCN →	+0.047	+5.539	<.001	.003	3	1
BLOOD_Leukemia	KRTAP5-3 →	+0.021	+4.922	.002	.009	3	1
BLOOD_Leukemia	CTXN3 →	+0.012	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

OR6T1 by MGAT4B expression — STOMACH

Explore this box plot interactively →