Across TCGA patient cohorts, MFSD6L mutation is significantly associated with the RNA expression of many other genes, with 3,436 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD6L-associated genes across cancer lineages are BTG3, NUDT2, and CENPU. Each is linked with MFSD6L in more than 2 cancer types. Because this analysis shows association rather than direction, both MFSD6L-to-partner and partner-to-MFSD6L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD6L→partner) and Y-score (partner→MFSD6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BTG3 →	+0.534	+3.807	.004	<.001	3	3
UCEC	NUDT2 →	+0.502	+2.617	.002	.005	3	3
UCEC	CENPU →	+0.884	+2.769	<.001	<.001	3	2
UCEC	AP1S3 →	+0.552	+1.901	.001	.004	3	2
UCEC	ATP5F1A →	+0.447	+3.397	.003	.004	3	2
UCEC	TRIM36 →	+0.834	+4.008	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,436 associations by consensus.

Exploration

MFSD6L survival (RNA) · tumor vs normal (RNA) · all MFSD6L data types