Across TCGA patient cohorts, MFSD6L mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD6L-associated genes across cancer lineages are mTOR_pS2448, p62 Lck ligand, and PCNA. Each is linked with MFSD6L in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD6L-to-partner and partner-to-MFSD6L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD6L→partner) and Y-score (partner→MFSD6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.202	-2.446	.001	.018	3	2
UCEC	p62 Lck ligand →	+0.398	+3.169	.005	.018	3	2
UCEC	PCNA →	+0.316	+2.115	<.001	.017	3	2
UCEC	c-Met_pY1235 →	+0.098	+2.125	.002	.010	3	2
UCEC	Cyclin-E2 →	+0.159	+2.115	.031	.019	3	2
UCEC	A-Raf_pS299 →	-0.151	-3.169	.003	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

MFSD6L survival (RNA) · tumor vs normal (RNA) · all MFSD6L data types