Across TCGA cell cohorts, MFSD6L mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFSD6L-associated genes across cancer lineages are IL2, DPT, and DEFA4. Each is linked with MFSD6L in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD6L-to-partner and partner-to-MFSD6L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD6L→partner) and Y-score (partner→MFSD6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IL2 →	+0.034	+3.700	<.001	.009	3	2
LARGE_INTESTINE	DPT →	+0.116	+3.333	.003	.009	3	1
LARGE_INTESTINE	DEFA4 →	+0.022	+3.700	<.001	.009	3	1
LARGE_INTESTINE	FOXI2 →	+0.013	+3.217	<.001	.006	3	1
LARGE_INTESTINE	OR51D1 →	+0.009	+3.217	<.001	.006	3	1
LARGE_INTESTINE	BPIFA1 →	+0.114	+4.009	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

MFSD6L survival (RNA) · tumor vs normal (RNA) · all MFSD6L data types