MFSD4B

Across TCGA patient cohorts, MFSD4B mutation is significantly associated with the RNA expression of many other genes, with 361 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD4B-associated genes across cancer lineages are TRGJP2, GBP5, and ABHD3. Each is linked with MFSD4B in more than 2 cancer types. Because this analysis shows association rather than direction, both MFSD4B-to-partner and partner-to-MFSD4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRGJP2 grouped by MFSD4B-low versus MFSD4B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD4B→partner) and Y-score (partner→MFSD4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRGJP2 →	+0.631	+2.811	<.001	.005	3	3
UCEC	GBP5 →	+1.048	+3.337	.002	.005	3	2
UCEC	ABHD3 →	+0.669	+3.480	.003	.002	3	2
UCEC	SLAMF6 →	+0.720	+3.584	.004	.002	3	2
UCEC	PBK →	+0.846	+2.233	.006	.006	3	2
UCEC	ZWILCH →	+0.581	+2.716	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 361 associations by consensus.

TRGJP2 by MFSD4B expression — COAD

Explore this box plot interactively →