MFSD4B

Across TCGA patient cohorts, MFSD4B mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MFSD4B-associated genes across cancer lineages are cDC, Adipocytes, and Macrophages M1. Each is linked with MFSD4B in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD4B-to-partner and partner-to-MFSD4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, cDC grouped by MFSD4B-low versus MFSD4B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD4B→partner) and Y-score (partner→MFSD4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	cDC →	+0.103	+3.026	.001	.019	3	2
COAD	Adipocytes →	+0.071	+2.431	<.001	.013	3	1
COAD	Macrophages M1 →	+0.029	+3.026	.001	.019	3	1
LUSC	Eosinophils →	+0.032	+2.588	.005	.036	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

cDC by MFSD4B expression — COAD

Explore this box plot interactively →