MFSD4B

Across TCGA cell cohorts, MFSD4B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,737 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFSD4B-associated GO terms across cancer lineages are Mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication, Hair follicle placode formation, and Phosphatidylinositol biosynthetic process. Each is linked with MFSD4B in more than 13 cancer types. Because this analysis shows association rather than direction, both MFSD4B-to-partner and partner-to-MFSD4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication grouped by MFSD4B-low versus MFSD4B-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD4B→partner) and Y-score (partner→MFSD4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication →	+0.119	+0.806	<.001	<.001	3	14
BLOOD_Myeloma	Hair follicle placode formation →	+0.069	+0.636	.004	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol biosynthetic process →	+0.054	+0.626	.001	<.001	3	14
PANCREAS	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.111	+0.682	<.001	<.001	3	13
BONE	Late viral transcription →	+0.136	+0.648	<.001	<.001	3	13
STOMACH	Cytosolic transport →	+0.099	+1.176	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,737 associations by consensus.

Mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication by MFSD4B expression — BLOOD_Lymphoma

Explore this box plot interactively →