MFSD14A

Across TCGA patient cohorts, MFSD14A mutation is significantly associated with the RNA expression of many other genes, with 1,959 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD14A-associated genes across cancer lineages are RNU6-68P, RPA2P1, and RNU6-978P. Each is linked with MFSD14A in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD14A-to-partner and partner-to-MFSD14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-68P grouped by MFSD14A-low versus MFSD14A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD14A→partner) and Y-score (partner→MFSD14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-68P →	+0.468	+6.721	<.001	<.001	3	2
BLCA	RPA2P1 →	+0.077	+6.147	<.001	.002	3	2
HNSC	RNU6-978P →	+0.347	+7.954	<.001	.008	3	2
HNSC	RNU1-139P →	+0.239	+7.954	<.001	.008	3	2
UCEC	RNA5SP414 →	+0.571	+2.177	<.001	<.001	3	2
UCEC	RNA5SP412 →	+0.633	+1.889	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,959 associations by consensus.

RNU6-68P by MFSD14A expression — COAD

Explore this box plot interactively →