MFSD11

Across TCGA cell cohorts, MFSD11 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MFSD11-associated genes across cancer lineages are OXT, GRM6, and RIPPLY1. Each is linked with MFSD11 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD11-to-partner and partner-to-MFSD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OXT grouped by MFSD11-low versus MFSD11-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD11→partner) and Y-score (partner→MFSD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OXT →	+0.044	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	GRM6 →	+0.032	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	RIPPLY1 →	+0.027	+4.191	.004	.007	3	1
BLOOD_Lymphoma	OR4N4 →	+0.055	+4.191	.007	.007	3	1
BLOOD_Lymphoma	TEX51 →	+0.019	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	GSTA2 →	+0.013	+5.169	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OXT by MFSD11 expression — BLOOD_Lymphoma

Explore this box plot interactively →