MFHAS1

Across TCGA cell cohorts, MFHAS1 mutation is significantly associated with the RNA expression of many other genes, with 418 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MFHAS1-associated genes across cancer lineages are DYNAP, TMEM38A, and APOC3. Each is linked with MFHAS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFHAS1-to-partner and partner-to-MFHAS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DYNAP grouped by MFHAS1-low versus MFHAS1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFHAS1→partner) and Y-score (partner→MFHAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DYNAP →	+0.269	+2.304	.009	.008	3	2
BLOOD_Leukemia	TMEM38A →	+1.044	+3.176	.002	.008	3	2
BLOOD_Leukemia	APOC3 →	+0.144	+2.668	<.001	.005	3	1
BLOOD_Leukemia	C8A →	+0.013	+2.877	<.001	.002	3	1
BLOOD_Leukemia	C1orf189 →	+0.125	+2.460	<.001	.004	3	1
BLOOD_Leukemia	WFDC12 →	+0.089	+2.482	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 418 associations by consensus.

DYNAP by MFHAS1 expression — BLOOD_Leukemia

Explore this box plot interactively →