MEX3B

Across TCGA cell cohorts, MEX3B mutation is significantly associated with the RNA expression of many other genes, with 330 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MEX3B-associated genes across cancer lineages are FAM47B, C9orf92, and GML. Each is linked with MEX3B in more than 1 cancer types. Because this analysis shows association rather than direction, both MEX3B-to-partner and partner-to-MEX3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47B grouped by MEX3B-low versus MEX3B-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEX3B→partner) and Y-score (partner→MEX3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	FAM47B →	+0.006	+5.369	<.001	.004	3	1
SOFT_TISSUE	C9orf92 →	+0.194	+5.369	<.001	.004	3	1
STOMACH	GML →	+0.043	+5.285	<.001	.003	3	1
LARGE_INTESTINE	GGA1 →	+0.716	+3.212	.001	.006	3	1
LARGE_INTESTINE	ANKRD54 →	+0.539	+3.299	.002	.004	3	1
LARGE_INTESTINE	CBY1 →	+0.744	+3.299	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 330 associations by consensus.

FAM47B by MEX3B expression — SOFT_TISSUE

Explore this box plot interactively →