METTL14-DT

Across TCGA patient cohorts, METTL14-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 9,106 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible METTL14-DT-associated proteins across cancer lineages are MYEF2, NELFE, and PGAM1_S31. Each is linked with METTL14-DT in more than 3 cancer types. Because this analysis shows association rather than direction, both METTL14-DT-to-partner and partner-to-METTL14-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METTL14-DT versus MYEF2 in HNSC, with a Pearson correlation of 0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL14-DT→partner) and Y-score (partner→METTL14-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYEF2 →	+1.024	+0.560	<.001	.006	3	4
LSCC	NELFE →	+0.213	+0.178	<.001	.001	3	4
BRCA	PGAM1_S31 →	-0.562	-0.312	<.001	<.001	3	3
BRCA	SDF2L1 →	-0.402	-0.299	<.001	<.001	3	3
LSCC	SRRT →	+0.196	+0.150	<.001	.009	3	3
LSCC	SUPT6H →	+0.249	+0.160	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,106 associations by consensus.

METTL14-DT vs MYEF2 — HNSC

Explore this scatter interactively →