METRN

Across TCGA patient cohorts, METRN RNA expression is significantly associated with the protein abundance of many other proteins, with 9,199 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible METRN-associated proteins across cancer lineages are STUB1, FLYWCH2, and GBP5. Each is linked with METRN in more than 6 cancer types. Because this analysis shows association rather than direction, both METRN-to-partner and partner-to-METRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METRN versus STUB1 in BRCA, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (METRN→partner) and Y-score (partner→METRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	STUB1 →	+0.512	+1.370	<.001	<.001	3	7
BRCA	FLYWCH2 →	+0.607	+1.687	<.001	<.001	3	5
HNSC	GBP5 →	-0.877	-0.594	.001	.006	3	4
BRCA	HAGH →	+0.269	+0.979	<.001	<.001	3	4
LUAD	STUB1_S273 →	+0.510	+0.735	<.001	.001	3	4
BRCA	MRTFB →	+0.413	+1.157	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,199 associations by consensus.

METRN vs STUB1 — BRCA

Explore this scatter interactively →