METAP1D

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, METAP1D protein abundance is significantly associated with the RNA expression of many other genes, with 5,568 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible METAP1D-associated genes across cancer lineages are RENBP, APOE, and TUBA1C. Each is linked with METAP1D in more than 2 cancer types. Because this analysis shows association rather than direction, both METAP1D-to-partner and partner-to-METAP1D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METAP1D versus RENBP in OV, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METAP1D→partner) and Y-score (partner→METAP1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRENBP →-0.861-0.486<.001<.00133
OVAPOE →-1.347-0.586<.001<.00133
OVTUBA1C →-0.741-0.491<.001.00433
LSCCC1QC →-0.817-0.341<.001<.00133
PDACTMEM97 →+0.876+0.295.001<.00133
LSCCMT-ND4L →+0.811+0.207<.001.00533
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,568 associations by consensus.

METAP1D vs RENBP — OV

Per-sample scatter of METAP1D vs RENBP in OV (Pearson r = -0.42).

Explore this scatter interactively →

Exploration