METAP1D

Across TCGA cell cohorts, METAP1D RNA expression is significantly associated with the go_rna of many other GO terms, with 3,538 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible METAP1D-associated GO terms across cancer lineages are tRNA methylation, Regulation of telomerase RNA localization to Cajal body, and Cell killing. Each is linked with METAP1D in more than 11 cancer types. Because this analysis shows association rather than direction, both METAP1D-to-partner and partner-to-METAP1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA methylation grouped by METAP1D-low versus METAP1D-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (METAP1D→partner) and Y-score (partner→METAP1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	tRNA methylation →	+0.067	+0.917	<.001	<.001	3	12
SOFT_TISSUE	Regulation of telomerase RNA localization to Cajal body →	+0.073	+0.977	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Cell killing →	-0.131	-1.269	<.001	<.001	3	11
BONE	Nucleic acid transport →	+0.104	+0.855	.006	.001	3	11
BONE	RNA transport →	+0.104	+0.855	.006	.001	3	11
BONE	Viral translational termination-reinitiation →	+0.090	+0.936	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,538 associations by consensus.

tRNA methylation by METAP1D expression — BLOOD_Lymphoma

Explore this box plot interactively →