MEOX2

Across TCGA cell cohorts, MEOX2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MEOX2-associated genes across cancer lineages are MMP27, AWAT2, and C10orf53. Each is linked with MEOX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MEOX2-to-partner and partner-to-MEOX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP27 grouped by MEOX2-low versus MEOX2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEOX2→partner) and Y-score (partner→MEOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MMP27 →	+0.015	+4.384	<.001	.006	3	1
BLOOD_Leukemia	AWAT2 →	+0.012	+3.705	<.001	.007	3	1
BLOOD_Leukemia	C10orf53 →	+0.186	+4.133	<.001	.003	3	1
LUNG_NSCLC_LUAD	CLRN1 →	+0.033	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	GPR101 →	+0.012	+4.887	.004	.009	3	1
LUNG_NSCLC_LUAD	OR4D5 →	+0.019	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

MMP27 by MEOX2 expression — BLOOD_Leukemia

Explore this box plot interactively →