MEGF11

Across TCGA patient cohorts, MEGF11 protein abundance is significantly associated with the RNA expression of many other genes, with 915 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MEGF11-associated genes across cancer lineages are POLDIP3, ZC3H7B, and BRD1. Each is linked with MEGF11 in more than 1 cancer types. Because this analysis shows association rather than direction, both MEGF11-to-partner and partner-to-MEGF11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEGF11 versus POLDIP3 in LUAD, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF11→partner) and Y-score (partner→MEGF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	POLDIP3 →	+0.391	+2.634	.009	<.001	3	1
LUAD	ZC3H7B →	+0.613	+2.557	.006	<.001	3	1
LUAD	BRD1 →	+0.431	+1.728	.008	.006	3	1
LUAD	SLC10A1 →	+0.518	+1.987	.008	<.001	3	1
LUAD	EEF1AKNMT →	+0.537	+2.037	.001	<.001	3	1
LUAD	CCDC130 →	+0.585	+2.472	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 915 associations by consensus.

MEGF11 vs POLDIP3 — LUAD

Explore this scatter interactively →