MEGF11

Across TCGA cell cohorts, MEGF11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,595 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MEGF11-associated GO terms across cancer lineages are Lipoprotein localization, Lipoprotein transport, and Regulation of transcription initiation by RNA polymerase II. Each is linked with MEGF11 in more than 9 cancer types. Because this analysis shows association rather than direction, both MEGF11-to-partner and partner-to-MEGF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipoprotein localization grouped by MEGF11-low versus MEGF11-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF11→partner) and Y-score (partner→MEGF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Lipoprotein localization →	+0.103	+0.619	<.001	.003	3	10
LUNG_NSCLC_LUSC	Lipoprotein transport →	+0.136	+0.602	<.001	.004	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.055	+0.198	<.001	<.001	3	8
BLOOD_Lymphoma	Positive regulation of DNA repair →	+0.060	+1.802	<.001	<.001	3	8
BLOOD_Leukemia	Positive regulation of DNA metabolic process →	+0.042	+0.699	<.001	.002	3	8
BLOOD_Leukemia	Protein localization to microtubule organizing center →	+0.025	+0.636	.009	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,595 associations by consensus.

Lipoprotein localization by MEGF11 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →