MED28P8

Across TCGA pan-cancer cohorts, MED28P8 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated MED28P8 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher MED28P8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MED28P8 expression acts as an unfavorable survival marker, although some lineages such as OV and BLCA show a favorable association.

READ, HNSC, and COAD are the cancer types where MED28P8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	II,III,IV	0.305	0.850	<.001	90	view →
HNSC	OS	Tertile	III,IV	0.428	0.672	.007	48	view →
COAD	OS	Tertile	II,III,IV	0.635	0.863	.005	42	view →
OV	DFS	Tertile	III,IV	0.211	0.141	.018	42	view →
KIRC	DFS	Tertile	III,IV	0.317	0.513	.009	36	view →
UCEC	OS	Tertile	III,IV	0.394	0.629	.013	30	view →
BLCA	DFS	Tertile	All	1.000	0.287	.022	27	view →
SARC	OS	Tertile	All	0.743	0.856	.009	18	view →
LUAD	DFS	Tertile	II,III,IV	0.344	0.551	.024	18	view →
ACC	OS	Tertile	IV	0.251	0.743	<.001	18	view →
BRCA	OS	Tertile	III,IV	0.669	0.838	.037	6	view →
ESCA	OS	Quartile	III,IV	0.691	0.344	.037	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

MED28P8–READ (OS)

Open the READ breakdown →