MED18

Across TCGA patient cohorts, MED18 protein abundance is significantly associated with the RNA expression of many other genes, with 10,264 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED18-associated genes across cancer lineages are OIP5, BYSL, and CBX2. Each is linked with MED18 in more than 4 cancer types. Because this analysis shows association rather than direction, both MED18-to-partner and partner-to-MED18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED18 versus OIP5 in LUAD, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED18→partner) and Y-score (partner→MED18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OIP5 →	+0.499	+0.282	.001	.005	2	5
LSCC	BYSL →	+0.612	+0.280	<.001	<.001	3	4
LSCC	CBX2 →	+0.994	+0.225	<.001	<.001	3	4
LSCC	TLR10 →	-0.810	-0.308	<.001	<.001	3	4
LSCC	KIAA0100 →	+0.623	+0.360	<.001	<.001	3	4
PDAC	PGR →	-0.574	-0.257	<.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,264 associations by consensus.

MED18 vs OIP5 — LUAD

Explore this scatter interactively →