MED18

Across TCGA cell cohorts, MED18 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,266 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MED18-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Positive regulation of mRNA catabolic process, and DAMP biosynthetic process. Each is linked with MED18 in more than 8 cancer types. Because this analysis shows association rather than direction, both MED18-to-partner and partner-to-MED18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by MED18-low versus MED18-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED18→partner) and Y-score (partner→MED18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of organelle assembly →	+0.060	+0.404	.007	.007	1	9
BONE	Positive regulation of mRNA catabolic process →	+0.047	+0.435	.004	.004	3	7
BONE	DAMP biosynthetic process →	+0.133	+0.481	<.001	.003	3	7
BONE	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.133	+0.481	<.001	.003	3	7
LARGE_INTESTINE	Autophagosome organization →	+0.047	+0.654	.003	<.001	2	8
BLOOD_Leukemia	Mitotic nuclear division →	+0.057	+0.380	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,266 associations by consensus.

Positive regulation of organelle assembly by MED18 expression — BONE

Explore this box plot interactively →