MED16

Across TCGA patient cohorts, MED16 protein abundance is significantly associated with the RNA expression of many other genes, with 15,012 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED16-associated genes across cancer lineages are CDCA3, CEP72, and SMC4. Each is linked with MED16 in more than 5 cancer types. Because this analysis shows association rather than direction, both MED16-to-partner and partner-to-MED16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED16 versus CDCA3 in BRCA, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED16→partner) and Y-score (partner→MED16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDCA3 →	+0.773	+0.235	<.001	<.001	3	6
HNSC	CEP72 →	+1.033	+0.207	<.001	<.001	3	6
LSCC	SMC4 →	+0.699	+0.152	<.001	<.001	3	6
GBM	NCAPH →	+0.736	+0.203	<.001	<.001	3	6
UCEC	KIF18A →	+0.751	+0.140	<.001	.001	3	6
UCEC	TOP2A →	+1.061	+0.132	.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,012 associations by consensus.

MED16 vs CDCA3 — BRCA

Explore this scatter interactively →