MEAK7

Across TCGA cell cohorts, MEAK7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,656 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MEAK7-associated GO terms across cancer lineages are Negative regulation of cilium assembly, Symbiont entry into host, and Symbiont entry into host cell. Each is linked with MEAK7 in more than 15 cancer types. Because this analysis shows association rather than direction, both MEAK7-to-partner and partner-to-MEAK7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cilium assembly grouped by MEAK7-low versus MEAK7-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEAK7→partner) and Y-score (partner→MEAK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of cilium assembly →	+0.097	+1.844	.001	<.001	3	15
BONE	Symbiont entry into host →	+0.120	+1.314	.004	.005	3	15
BONE	Symbiont entry into host cell →	+0.120	+1.314	.004	.005	3	15
LUNG_NSCLC_LUSC	Cellular response to environmental stimulus →	+0.052	+1.572	.003	.004	1	16
BONE	Regulation of cell-substrate adhesion →	+0.132	+1.165	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of protein localization to lysosome →	+0.232	+1.991	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,656 associations by consensus.

Negative regulation of cilium assembly by MEAK7 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →