MEAK7

Across TCGA cell cohorts, MEAK7 mutation is significantly associated with the RNA expression of many other genes, with 212 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MEAK7-associated genes across cancer lineages are KRTAP10-7, GCAT, and ETV7. Each is linked with MEAK7 in more than 1 cancer types. Because this analysis shows association rather than direction, both MEAK7-to-partner and partner-to-MEAK7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-7 grouped by MEAK7-low versus MEAK7-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEAK7→partner) and Y-score (partner→MEAK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	KRTAP10-7 →	+0.026	+5.285	<.001	.003	3	1
LARGE_INTESTINE	GCAT →	+1.752	+3.212	<.001	.006	3	1
LARGE_INTESTINE	ETV7 →	+1.130	+3.212	.003	.006	3	1
LARGE_INTESTINE	IL27RA →	+1.139	+3.212	.001	.006	3	1
LARGE_INTESTINE	C1QBP →	+0.830	+3.299	<.001	.004	3	1
LARGE_INTESTINE	DNAJC16 →	+0.690	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 212 associations by consensus.

KRTAP10-7 by MEAK7 expression — STOMACH

Explore this box plot interactively →