MDFI

Across TCGA patient cohorts, MDFI RNA expression is significantly associated with the protein abundance of many other proteins, with 16,231 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MDFI-associated proteins across cancer lineages are FSCN1, MMP14, and PLAU. Each is linked with MDFI in more than 7 cancer types. Because this analysis shows association rather than direction, both MDFI-to-partner and partner-to-MDFI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MDFI versus FSCN1 in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MDFI→partner) and Y-score (partner→MDFI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FSCN1 →	+0.571	+1.207	<.001	<.001	3	8
OV	MMP14 →	+0.584	+1.498	<.001	<.001	3	7
COAD	PLAU →	+0.907	+1.250	<.001	<.001	3	7
OV	P3H3 →	+0.713	+1.291	<.001	<.001	3	7
UCEC	AFAP1_S668 →	+0.679	+1.532	<.001	<.001	3	6
OV	CNN2 →	+0.858	+1.487	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,231 associations by consensus.

MDFI vs FSCN1 — HNSC

Explore this scatter interactively →