MCM3

Across TCGA cell cohorts, MCM3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,786 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MCM3-associated genes across cancer lineages are RUNX2, ULBP2, and LAMC1. Each is linked with MCM3 in more than 5 cancer types. Because this analysis shows association rather than direction, both MCM3-to-partner and partner-to-MCM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCM3 versus RUNX2 in BLOOD_Lymphoma, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCM3→partner) and Y-score (partner→MCM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	RUNX2 →	+3.075	+0.984	.004	.005	3	5
BREAST	ULBP2 →	+2.691	+2.075	.006	<.001	3	5
BREAST	LAMC1 →	+1.730	+1.148	.003	.008	3	5
BREAST	IGFBP6 →	+3.453	+1.286	.001	.003	3	5
BREAST	MCAM →	+3.691	+1.681	.001	.003	3	5
PANCREAS	KDM2B →	-0.805	-1.116	.008	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,786 associations by consensus.

MCM3 vs RUNX2 — BLOOD_Lymphoma

Explore this scatter interactively →