Across TCGA patient cohorts, MBLAC1 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MBLAC1-associated genes across cancer lineages are PCNPP2, LINC02699, and CYP4F9P. Each is linked with MBLAC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MBLAC1-to-partner and partner-to-MBLAC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBLAC1→partner) and Y-score (partner→MBLAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNPP2 →	+0.193	+6.226	<.001	.001	3	2
BLCA	LINC02699 →	+0.361	+3.642	<.001	.009	3	1
BLCA	CYP4F9P →	+0.036	+4.213	.001	.003	3	1
UCEC	MIR6749 →	+0.809	+5.186	<.001	.007	3	1
UCEC	MIR8058 →	+0.658	+5.081	.007	.008	3	1
COAD	PRSS40B →	+0.014	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

MBLAC1 survival (RNA) · tumor vs normal (RNA) · all MBLAC1 data types