Across TCGA pan-cancer cohorts, MBLAC1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated MBLAC1 data layer compared with 1 for mutation status and 2 for mass-spec protein.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MBLAC1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MBLAC1 expression acts as an unfavorable survival marker, although some lineages such as OV and PAAD show a favorable association.
LUAD, ACC, and OV are the cancer types where MBLAC1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.