Across TCGA pan-cancer cohorts, MBL3P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MBL3P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MBL3P RNA is repressed in tumor relative to normal tissue. In most cancer types MBL3P is over-expressed in tumor, although a few such as LUSC and BRCA show the opposite, repressed pattern.

LUSC, BRCA, and LUAD are the cancer types where MBL3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MBL3P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	II,III,IV	−0.565	<.001	6	view →
BRCA	All	III,IV	−0.195	<.001	6	view →
LUAD	All	II,III,IV	−0.399	.015	3	view →
KICH	All	All	−0.040	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MBL3P RNA expression & survival · all MBL3P data types