MBL1P

Across TCGA patient cohorts, MBL1P mutation is significantly associated with the RNA expression of many other genes, with 1,055 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MBL1P-associated genes across cancer lineages are LIN37, PCGF7P, and RPARP-AS1. Each is linked with MBL1P in more than 1 cancer types. Because this analysis shows association rather than direction, both MBL1P-to-partner and partner-to-MBL1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIN37 grouped by MBL1P-low versus MBL1P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBL1P→partner) and Y-score (partner→MBL1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LIN37 →	+0.516	+3.480	<.001	.002	3	2
UCEC	PCGF7P →	+0.194	+3.475	<.001	.002	3	2
UCEC	RPARP-AS1 →	+0.703	+3.491	<.001	.002	3	2
UCEC	MED19 →	+0.499	+3.332	<.001	.005	3	2
UCEC	DBF4B →	+0.475	+2.524	.008	.009	3	2
UCEC	SUGT1 →	+0.418	+3.508	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,055 associations by consensus.

LIN37 by MBL1P expression — UCEC

Explore this box plot interactively →