MBL1P

Across TCGA pan-cancer cohorts, MBL1P RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of MBL1P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MBL1P RNA is repressed in tumor relative to normal tissue. In most cancer types MBL1P is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and LUSC are the cancer types where MBL1P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MBL1P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	−0.818	<.001	12	view →
KICH	Female	II,III,IV	−1.708	<.001	10	view →
LUSC	Female	II,III,IV	−1.967	<.001	9	view →
LUAD	Female	III,IV	−1.644	<.001	9	view →
THCA	All	II,III,IV	+0.466	<.001	9	view →
KIRP	All	All	−0.848	<.001	7	view →
BRCA	All	All	−0.313	<.001	6	view →
CHOL	All	All	−0.680	<.001	2	view →
LIHC	Female	All	−0.442	.001	2	view →
BLCA	Female	All	−0.343	.030	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

MBL1P–KIRC

Open the KIRC breakdown →