Across TCGA cell cohorts, MBD3L4 RNA expression is significantly associated with the mutation status of many other genes, with 98 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MBD3L4-associated genes across cancer lineages are STAG2, ADAMTS8, and PRKCB. Each is linked with MBD3L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MBD3L4-to-partner and partner-to-MBD3L4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MBD3L4→partner) and Y-score (partner→MBD3L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	STAG2 →	+4.087	+0.020	.009	<.001	3	2
LUNG_NSCLC_LUAD	ADAMTS8 →	+4.266	+0.011	.004	<.001	3	2
LUNG_NSCLC_LUAD	PRKCB →	+4.681	+0.013	.003	<.001	3	2
URINARY_TRACT	RECK →	+4.087	+0.020	.009	<.001	3	1
URINARY_TRACT	MSRB2 →	+5.087	+0.026	.004	<.001	3	1
URINARY_TRACT	CKAP5 →	+5.087	+0.026	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 98 associations by consensus.

Exploration

MBD3L4 survival (RNA) · tumor vs normal (RNA) · all MBD3L4 data types